SCHEMBL28993186

SCHEMBL28993186

COc1ccc(OC(C)(C)C(C)(C)O)cc1.OBO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA14 Q9ULX7 1/20 0.44
AOC3 Q16853 1/20 0.39
ACHE P22303 1/20 0.38
LTA4H P09960 1/20 0.38
ESR2 Q92731 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
ELANE P08246 1/20 0.38
ENPP2 Q13822 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
MAPK1 P28482 2/20 0.37
PDK1 Q15118 1/20 0.37
PDK2 Q15119 1/20 0.37
PDK3 Q15120 1/20 0.37
PDK4 Q16654 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920698 0.94 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL17312043 0.92 CA1 (0.48) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL4957328 0.78 CA1 (0.73) CA1CA2CA7CA9CA12
SCHEMBL17101177 0.75 GAA (0.44) CA1CA2CA9ACHECES2
SCHEMBL17312049 0.75 ALDH1A1 (0.48) CA1CA2MAPK1MAPTKDM4E
SCHEMBL27862358 0.75 ALDH1A1 (0.45) TDP1MAPK1MAPTNPC1GAA
SCHEMBL17312045 0.73 ACHE (0.44) CA1CA2CA7CA9ACHE
SCHEMBL21013230 0.73 CA1 (0.41) CA1CA2CA7CA9CA12
SCHEMBL1542267 0.72 MAPT (0.61) CA1CA2CA7CA9CA12
SCHEMBL1022162 0.72 CA4 (0.39) LTA4HMAPK1PDK1PDK2PDK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed