Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 14/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133 | 0.93 | CCR4 (0.66) | CCR4KDM4E | |
| SCHEMBL31027 | 0.83 | CCR4 (0.47) | CCR4 | |
| SCHEMBL29981 | 0.82 | CCR4 (0.58) | CCR4 | |
| SCHEMBL30260 | 0.81 | CCR4 (0.70) | CCR4KDM4E | |
| SCHEMBL29636 | 0.81 | CCR4 (0.57) | CCR4 | |
| SCHEMBL30317 | 0.79 | CCR4 (0.65) | CCR4 | |
| SCHEMBL28478 | 0.79 | CCR4 (0.65) | CCR4 | |
| SCHEMBL30582 | 0.77 | CCR4 (0.69) | CCR4KDM4E | |
| SCHEMBL29905 | 0.76 | CCR4 (0.54) | CCR4 | |
| SCHEMBL30601 | 0.74 | CCR4 (0.67) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |