Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607643 | 1.00 | MAPT (0.33) | MAPTALDH1A1RAB9AFBP1SLC6A2 | |
| SCHEMBL28994117 | 0.85 | BRAF (0.32) | MAPTALDH1A1RAB9AFBP1BRAF | |
| SCHEMBL25607648 | 0.85 | BRAF (0.32) | MAPTALDH1A1RAB9AFBP1BRAF | |
| SCHEMBL24618692 | 0.83 | SLC6A2 (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL25607598 | 0.83 | MAPT (0.37) | MAPTALDH1A1RAB9AFBP1KDM4E | |
| SCHEMBL28994477 | 0.80 | FBP1 (0.35) | MAPTALDH1A1FBP1KDM4E | |
| SCHEMBL25607652 | 0.80 | MAPT (0.36) | MAPTALDH1A1RAB9AFBP1BRAF | |
| SCHEMBL28994121 | 0.80 | MAPT (0.36) | MAPTALDH1A1RAB9AFBP1BRAF | |
| SCHEMBL25213136 | 0.69 | TLR4 (0.33) | MAPTALDH1A1FBP1NLRP3KDM4E | |
| SCHEMBL24618613 | 0.68 | XDH (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |