Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490958 | 0.84 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL17488990 | 0.76 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL11340426 | 0.76 | KCNH2 (0.56) | KCNH2BTK | |
| SCHEMBL30320172 | 0.75 | KCNH2 (0.35) | KCNH2BTK | |
| SCHEMBL24618685 | 0.75 | KCNH2 (0.35) | KCNH2BTK | |
| SCHEMBL9193789 | 0.73 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL22598222 | 0.73 | ALDH1A1 (0.42) | KCNH2BTK | |
| SCHEMBL8847307 | 0.73 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL29898877 | 0.72 | HRH1 (0.42) | KCNH2BTK | |
| SCHEMBL27800459 | 0.72 | KCNH2 (0.35) | KCNH2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |