Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968503 | 0.90 | ALOX15 (0.60) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL17392022 | 0.89 | DEGS1 (0.62) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL30050714 | 0.87 | GRM5 (0.53) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL28994215 | 0.87 | BTK (0.53) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL26075655 | 0.87 | NPC1 (0.60) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL16604279 | 0.87 | SORT1 (0.60) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL28953974 | 0.87 | PTGS1 (0.67) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL16594252 | 0.87 | GRM5 (0.53) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL28994195 | 0.87 | GRM5 (0.53) | BTKSORT1GRM5ALOX15TSHR | |
| SCHEMBL16835150 | 0.85 | BTK (0.52) | BTKSORT1GRM5ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |