SCHEMBL2899441

SCHEMBL2899441

O=C(OCc1ccccc1)[C@@H]1C[C@@H](O)CN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.50
▸ FABP5 Q01469 3/20 0.41
▸ FABP7 O15540 2/20 0.41
▸ FKBP1A P62942 5/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ EPHX2 P34913 1/20 0.38
▸ OPRD1 P41143 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ PSEN1 P49768 1/20 0.37
▸ PSEN2 P49810 1/20 0.37
▸ APH1B Q8WW43 1/20 0.37
▸ NCSTN Q92542 1/20 0.37
▸ APH1A Q96BI3 1/20 0.37
▸ PSENEN Q9NZ42 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30089351 1.00 POLB (0.50) POLBFABP5FABP7FKBP1AKMT2A
SCHEMBL2678864 0.87 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL7433978 0.87 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL23485199 0.87 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL30564487 0.87 POLB (0.61) POLBFKBP1APSEN1PSEN2APH1B
SCHEMBL1335555 0.86 FABP5 (0.46) POLBFABP5FABP7KMT2AEPHX2
SCHEMBL1000852 0.86 FABP5 (0.46) POLBFABP5FABP7KMT2AEPHX2
SCHEMBL4612189 0.86 FABP5 (0.46) POLBFABP5FABP7KMT2AEPHX2
SCHEMBL1336708 0.86 FABP5 (0.46) POLBFABP5FABP7KMT2AEPHX2
SCHEMBL31689008 0.86 FABP5 (0.46) POLBFABP5FABP7KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
US-7807678-B2 Peptidomimetics of biologically active metallopeptides PALATIN TECHNOLOGIES, INC. (US) 2010-10-05 — — US disclosed
US-7601753-B2 Pyrrolidine melanocortin-specific compounds PALATIN TECHNOLOGIES, INC. (US) 2009-10-13 — — US disclosed
US-20070155670-A1 Pyrrolidine Melanocortin-Specific Compounds PALATIN TECHNOLOGIES, INC. (US) 2007-07-05 — — US disclosed
US-7189755-B2 Pyrrolidine melanocortin-specific compounds PALATIN TECHNOLOGIES, INC. (US) 2007-03-13 — — US disclosed
EP-1425029-A4 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES INC (US) 2006-06-07 — — EP disclosed
US-20040171520-A1 Peptidomimetics of biologically active metallopeptides PALATIN TECHNOLOGIES, INC. 2004-09-02 — — US disclosed
US-20040167201-A1 Pyrrolidine melanocortin-specific compounds PALATIN TECHNOLOGIES, INC. (US) 2004-08-26 — — US disclosed
EP-1425029-A1 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES Palatin Technologies, Inc. (US) 2004-06-09 — — EP disclosed
WO-2003013571-A1 PEPTIDOMIMETICS OF BIOLOGICALLY ACTIVE METALLOPEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2003-02-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167201-A1 Pyrrolidine melanocortin-specific compounds MC3R, MC1R, MC5R POLB 2561/4885FABP5 3308/4885FABP7 1618/4885
US-20040171520-A1 Peptidomimetics of biologically active metallopeptides MC1R, MC4R, MC5R POLB 4167/4885FABP5 1044/4885FABP7 1213/4885
US-20070155670-A1 Pyrrolidine Melanocortin-Specific Compounds MC3R, MC1R, MC5R POLB 3019/4885FABP5 3849/4885FABP7 1613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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