Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL5359227 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL28098305 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL6370977 | 0.92 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| Cyclopentane SCHEMBL5157247 | 0.89 | — | — | |
| Ethylenediamine SCHEMBL69118 | 0.89 | — | — | |
| Ethylenediamine SCHEMBL9795508 | 0.89 | — | — | |
| Phosphonic Acid SCHEMBL3767316 | 0.86 | GLRA1 (0.33) | GLRA1SLC6A9OR51E2 | |
| Phosphonic Acid SCHEMBL31406934 | 0.86 | GLRA1 (0.33) | GLRA1SLC6A9OR51E2 | |
| Ethylenediamine SCHEMBL11090190 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL9798040 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539144-A | Dishwashing compositions with an anti-filming polymer | LEVER BROTHERS COMPANY (US) | 1985-09-03 | — | — | US | claimed |
| CN-117396758-A | Method for analyzing neuropeptide related to protein | 株式会社岛津制作所 | 2024-01-12 | — | — | CN | disclosed |
| CN-117157526-A | Method for producing standard curve and method for measuring amyloid-beta-related peptide | 株式会社岛津制作所 | 2023-12-01 | — | — | CN | disclosed |
| CN-116917727-A | Calibration material for use in mass spectrometry device and method for preparing same | 株式会社岛津制作所 | 2023-10-20 | — | — | CN | disclosed |
| CN-116891724-A | Polishing composition, polishing method, and method for producing semiconductor substrate | 福吉米株式会社 | 2023-10-17 | — | — | CN | disclosed |
| CN-116868057-A | Standard solution for quality control in peptide measurement and quality control for peptide measurement | 株式会社岛津制作所 | 2023-10-10 | — | — | CN | disclosed |
| CN-116745608-A | Analysis method | 株式会社岛津制作所 | 2023-09-12 | — | — | CN | disclosed |
| CN-116157894-A | Machine difference correction method for mass spectrum analysis device | 株式会社岛津制作所 | 2023-05-23 | — | — | CN | disclosed |
| CN-107106663-B | Compositions and kits for enzymatic debridement and methods of use thereof | 罗查尔科技有限责任公司 | 2022-12-06 | — | — | CN | disclosed |
| US-20210246334-A1 | POLISHING COMPOSITION, METHOD FOR PRODUCING POLISHING COMPOSITION, POLISHING METHOD, AND METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2021-08-12 | — | — | US | disclosed |
| EP-0550278-A1 | Detergent compositions comprising nonionic glycolipid surfactants | UNILEVER PLC (GB) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550277-A1 | Detergent compositions | UNILEVER PLC (GB) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550279-A1 | Compositions comprising a glyceroglycolipid | UNILEVER PLC (GB) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550280-A1 | Glycolipid surfactants and compositions containing them | UNILEVER PLC (GB) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550276-A1 | Compositions comprising anionic glycolipid surfactants | UNILEVER PLC (GB) | 1993-07-07 | — | — | EP | disclosed |
| US-4929379-A | Particulate detergent composition | LEVER BROTHERS COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4797352-A | FIXING LIQUID CONTAINING GUANIDINE, MORPHOLINE ETC. | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0117568-B1 | PARTICULATE DETERGENT COMPOSITION | UNILEVER N.V. (NL) | 1986-10-15 | — | — | EP | disclosed |
| EP-0117568-A1 | Particulate detergent composition | UNILEVER N.V. (NL) | 1984-09-05 | — | — | EP | disclosed |
| US-4298681-A | N,N Disubstituted p-phenylenediamine phosphates to form a color developer working solution, a color developer concentrate containing such a phosphate and a method of using said working solution for color development of color film | PHILIP A. HUNT CHEMICAL CORP. (US) | 1981-11-03 | — | — | US | disclosed |