SCHEMBL28995162

SCHEMBL28995162

C=C(C(=O)N(C)c1ccccc1Br)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.39
KMT2A Q03164 2/20 0.38
HPGD P15428 2/20 0.36
RAB9A P51151 3/20 0.35
ATM Q13315 2/20 0.35
NPC1 O15118 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RECQL P46063 1/20 0.34
TSPO P30536 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995156 0.81 ALDH1A1 (0.36) EGFRHPGDSMN1; SMN2MAPTTSPO
SCHEMBL28726963 0.81 EGFR (0.39) EGFRKMT2AHPGDRAB9AATM
SCHEMBL28867944 0.80 KMT2A (0.46) EGFRKMT2AHPGDRAB9ANPC1
SCHEMBL4660910 0.78 KMT2A (0.47) EGFRKMT2AHPGDRAB9AATM
SCHEMBL22507695 0.77 ESR1 (0.38) EGFRKMT2AHPGDRAB9ANPC1
SCHEMBL6219691 0.77 HPGD (0.46) HPGDRAB9ANPC1SMN1; SMN2MAPT
SCHEMBL28815033 0.75 HPGD (0.50) EGFRKMT2AHPGDRAB9AATM
SCHEMBL12550519 0.75 ALDH1A1 (0.47) KMT2AHPGDRAB9ANPC1SMN1; SMN2
SCHEMBL1628742 0.75 EGFR (0.48) EGFRKMT2AHPGDRAB9AATM
SCHEMBL22507696 0.74 KMT2A (0.33) EGFRKMT2AHPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116043243-B Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2025-02-18 CN disclosed
CN-116043243-A Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2023-05-02 CN disclosed