SCHEMBL4660910

SCHEMBL4660910

C=C(C(=O)N(C)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
KDM4E B2RXH2 1/20 0.47
EGFR P00533 2/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
HPGD P15428 1/20 0.44
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
ATM Q13315 1/20 0.41
FAAH O00519 1/20 0.41
PHGDH O43175 1/20 0.41
MGLL Q99685 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28250860 0.85 KDM4E (0.55) KMT2AKDM4ERAB9ANPC1HPGD
SCHEMBL1628742 0.82 EGFR (0.48) KMT2AEGFRRAB9ANPC1HPGD
SCHEMBL17704773 0.81 KMT2A (0.53) KMT2AKDM4ERAB9ANPC1MEN1
SCHEMBL28250855 0.81 LIPE (0.48) KMT2ARAB9ANPC1MEN1SMN1; SMN2
SCHEMBL194085 0.80 HTT (0.46) KMT2AKDM4ERAB9ANPC1MEN1
SCHEMBL5425617 0.80 NPSR1 (0.52) KMT2AEGFRRAB9ANPC1HPGD
SCHEMBL4022489 0.78 KMT2A (0.44) KMT2AKDM4ERAB9ANPC1MEN1
SCHEMBL28726963 0.78 EGFR (0.39) KMT2AEGFRRAB9ANPC1HPGD
SCHEMBL28995162 0.78 EGFR (0.39) KMT2AEGFRRAB9ANPC1HPGD
SCHEMBL9456596 0.77 KMT2A (0.50) KMT2AKDM4ERAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1776176-A4 COMPOSITE MATERIAL COMPRISING A NON-CROSSLINKED GEL POLYMER UNIV MCMASTER (CA) 2008-12-24 EP claimed
EP-1776176-A1 COMPOSITE MATERIAL COMPRISING A NON-CROSSLINKED GEL POLYMER McMaster University (CA) 2007-04-25 EP claimed
WO-2006015495-A1 COMPOSITE MATERIAL COMPRISING A NON-CROSSLINKED GEL POLYMER MCMASTER UNIVERSITY (CA) 2006-02-16 WO claimed
US-20250144853-A1 METHODS FOR MANUFACTURING AND DISTRIBUTING SEMI-RIGID ACOUSTIC COUPLING ARTICLES AND PACKAGING FOR ULTRASOUND IMAGING Decision Sciences Medical Company, LLC 2025-05-08 US disclosed
US-12017389-B2 Methods for manufacturing and distributing semi-rigid acoustic coupling articles and packaging for ultrasound imaging Decision Sciences Medical Company, LLC (US) 2024-06-25 US disclosed
CN-118221564-A Preparation method of branched-chain alcohol-containing hydroxy indolone 滁州学院 2024-06-21 CN disclosed
EP-4362856-A1 MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS Hyalex Orthopaedics, Inc. (US) 2024-05-08 EP disclosed
EP-4314164-A1 RUBBERIZED ASPHALT COMPOSITION WITH ACRYLIC COPOLYMER BASF SE (DE) 2024-02-07 EP disclosed
WO-2023278875-A1 MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS HYALEX ORTHOPAEDICS, INC. (US) 2023-01-05 WO disclosed
US-20220134608-A1 METHODS FOR MANUFACTURING AND DISTRIBUTING SEMI-RIGID ACOUSTIC COUPLING ARTICLES AND PACKAGING FOR ULTRASOUND IMAGING Decision Sciences Medical Company, LLC 2022-05-05 US disclosed
US-20220106424-A1 HYDROGEL COMPOSITION FOR A SEMI-RIGID ACOUSTIC COUPLING MEDIUM IN ULTRASOUND IMAGING Decision Sciences Medical Company, LLC 2022-04-07 US disclosed
US-8569405-B2 Additive mixtures for styrenic polymers BASF SE (DE) 2013-10-29 US disclosed
WO-2013052105-A2 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE BIOMIMEDICA, INC. (US) 2013-04-11 WO disclosed
EP-2238199-B1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (DE) 2011-08-31 EP disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
US-20110046278-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (US) 2011-02-24 US disclosed
WO-2009095328-A1 ADDITIVE MIXTURES FOR STYRENIC POLYMERS BASF SE (DE) 2009-08-06 WO disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 KMT2A 1853/4885KDM4E 2115/4885EGFR 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.