SCHEMBL28995206

SCHEMBL28995206

CNC(=O)n1c(NC(=O)O)nc2c(C)cccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.36
NPC1 O15118 5/20 0.36
RAB9A P51151 5/20 0.36
LMNA P02545 3/20 0.36
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 2/20 0.34
HTT P42858 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TSHR P16473 1/20 0.34
ASAH1 Q13510 1/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
HIF1A Q16665 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPSE Q9Y251 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716174 0.81 TSHR (0.56) ALDH1A1KMT2AHTTSMN1; SMN2TSHR
SCHEMBL26619060 0.80 TSHR (0.51) NPC1RAB9ALMNAALDH1A1MAPT
SCHEMBL11626517 0.70 TSHR (0.47) EGFRNPC1RAB9ALMNAALDH1A1
SCHEMBL15112010 0.67 KMT2A (0.40) ALDH1A1KMT2AMEN1
SCHEMBL15730166 0.67 HSD17B10 (0.40) EGFRNPC1RAB9ALMNAKMT2A
SCHEMBL20371600 0.67 KDM4E (0.39) EGFRALDH1A1MAPTKMT2AGAA
SCHEMBL202952 0.67 ALDH1A1 (0.68) NPC1RAB9ALMNAALDH1A1MAPT
SCHEMBL27197724 0.66 TSHR (0.60) NPC1RAB9ALMNAALDH1A1KMT2A
Hydrochloric Acid SCHEMBL28791312 0.66 KMT2A (0.39) ALDH1A1KMT2AMEN1
SCHEMBL18764950 0.66 PPARG (0.42) ALDH1A1KMT2AMEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272363-B Silicone-organic copolymers, sealants including silicone-organic copolymers, and related methods 美国陶氏有机硅公司 2023-02-17 CN disclosed