Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982821 | 0.74 | POLB (0.36) | POLBHTTALDH1A1MAPT | |
| SCHEMBL24463145 | 0.73 | CA1 (0.32) | ALDH1A1 | |
| SCHEMBL30490178 | 0.73 | CA1 (0.32) | ALDH1A1 | |
| SCHEMBL15556916 | 0.72 | HTT (0.39) | POLBHTTNOS3NOS1NOS2 | |
| SCHEMBL28176866 | 0.70 | HTT (0.41) | POLBHTTNOS3NOS1NOS2 | |
| SCHEMBL832574 | 0.69 | ALDH1A1 (0.43) | POLBHTTNOS3NOS1NOS2 | |
| SCHEMBL29639033 | 0.69 | PTK2 (0.44) | POLBHTTNOS3NOS1NOS2 | |
| SCHEMBL5951845 | 0.69 | PTK2 (0.44) | POLBHTTNOS3NOS1NOS2 | |
| SCHEMBL31285294 | 0.68 | MAPK14 (0.43) | MAPT | |
| SCHEMBL16868362 | 0.67 | DPP4 (0.36) | POLBHTTNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |