SCHEMBL5951845

SCHEMBL5951845

CCc1cc(N)c(N)cc1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.44
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
POLB P06746 2/20 0.41
HTT P42858 2/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 3/20 0.37
ALOX12 P18054 1/20 0.37
AR P10275 1/20 0.36
CYP1A2 P05177 1/20 0.36
CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29639033 1.00 PTK2 (0.44) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11468902 0.88 AR (0.42) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL832574 0.87 ALDH1A1 (0.43) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13375163 0.87 GRIA1 (0.38) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3107558 0.85 GRIN2D (0.37) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5951712 0.83 ALDH1A1 (0.52) PTK2POLBHTTNOS3NOS1
SCHEMBL13375174 0.83 POLB (0.36) PTK2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5382583 0.81 AR (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8729779 0.81 ALDH1A1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10545243 0.81 POLB (0.38) PTK2GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024038810-A1 POSITIVE-TYPE PHOTOSENSITIVE COMPOSITION, CURED FILM, ORGANIC EL DISPLAY DEVICE, AND COLORANT 東レ株式会社 2024-02-22 WO disclosed
CN-117043676-A Positive photosensitive pigment composition, cured film containing cured product thereof, and organic EL display device 东丽株式会社 2023-11-10 CN disclosed
WO-2022270182-A1 POSITIVE PHOTOSENSITIVE PIGMENT COMPOSITION, CURED FILM CONTAINING CURED PRODUCT THEREOF, AND ORGANIC EL DISPLAY DEVICE 東レ株式会社 2022-12-29 WO disclosed
CN-113087674-B Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer 河南大学 2022-06-17 CN disclosed
CN-113087674-A Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition 河南大学 2021-07-09 CN disclosed
US-20120277433-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED QUINOXALINES ALKEM LABORATORIES LIMITED (IN) 2012-11-01 US disclosed
US-8288425-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2012-10-16 US disclosed
US-8288425-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2012-10-16 US disclosed
US-8288425-B2 Benzimidazoles AVENTIS PHARMACEUTICALS INC. (US) 2012-10-16 US disclosed
US-20080275051-A1 Preparation of High Purity Substituted Quinoxalines BUSCH FRANK R 2008-11-06 US disclosed
US-5795889-A INHIBITING CELL GROWTH WITH ENZYME INHIBITORS FOR SKIN DISORDERS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-08-18 US disclosed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US disclosed
US-5646153-A INHIBITING ABNORMAL CELL PROLIFERATION RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-08 US disclosed
US-5631373-A NERVOUS SYSTEM DISORDERS STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-05-20 US disclosed
EP-0770688-A1 Method of quantitative determination of bilirubin and a reagent therefor KYOWA MEDEX CO., LTD. (JP) 1997-05-02 EP disclosed
EP-0732942-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1996-09-25 EP disclosed
EP-0718666-A1 Liquid crystal-aligning agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-26 EP disclosed
US-5480883-A Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-01-02 US disclosed
WO-1995012417-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1995-05-11 WO disclosed
US-4301171-A 2-(1,4-Benzodioxan-2-ylalkyl)benzimidazoles useful as anti-depressants SYNTEX (U.S.A.) INC. (US) 1981-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275051-A1 Preparation of High Purity Substituted Quinoxalines QDPR, NQO2, NDUFA7 PTK2 4071/4885GRIN2D 1308/4885GRIN3B 1769/4885
US-20120277433-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED QUINOXALINES QDPR, DCXR, NQO2 PTK2 3398/4885GRIN2D 1062/4885GRIN3B 1362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.