Methane

Methane

SCHEMBL28995945

C.COc1ccc(-c2cc(Br)ccc2Cl)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
PRKAB2 O43741 3/20 0.42
PRKAG1 P54619 3/20 0.42
PRKAA2 P54646 3/20 0.42
PRKAA1 Q13131 3/20 0.42
PRKAG3 Q9UGI9 3/20 0.42
PRKAG2 Q9UGJ0 3/20 0.42
PRKAB1 Q9Y478 3/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29817108 0.98 ABL1 (0.44) MEN1KMT2AABL1ABCB1BCR
SCHEMBL7777278 0.83 HSP90AA1 (0.50) ABL1ABCB1BCRPRKAB2PRKAG1
SCHEMBL29669964 0.81 SMN1; SMN2 (0.44) KMT2ALMNAMAPTMAPK1NPSR1
SCHEMBL7777203 0.81 ESR2 (0.57) MEN1KMT2AABL1ABCB1BCR
SCHEMBL29473775 0.80 CA1 (0.51) MEN1KMT2AABL1ABCB1BCR
SCHEMBL29893480 0.80 FFAR4 (0.56) MEN1KMT2APRKAB2PRKAG1PRKAA2
SCHEMBL7771075 0.77 ESR2 (0.57) MEN1KMT2AABL1ABCB1BCR
SCHEMBL30423821 0.76 PREP (0.42) MEN1KMT2ALMNAMAPTNPSR1
Formaldehyde SCHEMBL29161042 0.76 FFAR4 (0.55) MEN1KMT2APRKAB2PRKAG1PRKAA2
SCHEMBL29041284 0.76 ALOX15 (0.48) MEN1KMT2AABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756611-A Preparation method of dapagliflozin intermediate 山东新时代药业有限公司 2024-03-26 CN disclosed
CN-108285439-B Carbonoside sodium glucose transport protein body 2 inhibitor 江苏天士力帝益药业有限公司 2023-05-02 CN disclosed