SCHEMBL2899697

SCHEMBL2899697

CC(=O)NC[C@H]1CN(c2ccc(-c3cnc(-n4ccnn4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 15/20 0.60
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MAOB P27338 2/20 0.53
LMNA P02545 1/20 0.53
PTGS1 P23219 1/20 0.53
CALML3 P27482 1/20 0.53
SDHA P31040 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793468 0.91 MAOA (0.62) MAOACYP3A4CYP2D6
SCHEMBL2890962 0.89 MAOA (0.49) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL2895221 0.89 MAOA (0.59) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL5805368 0.89 MAOA (0.59) MAOAMAOBLMNAPTGS1CALML3
SCHEMBL2894876 0.87 MAOA (0.62) MAOACYP3A4MAOBLMNAPTGS1
SCHEMBL2893778 0.85 MAOA (0.59) MAOACYP3A4MAOBLMNAPTGS1
SCHEMBL2898208 0.85 MAOA (0.59) MAOACYP3A4MAOBLMNAPTGS1
SCHEMBL2897655 0.85 MAOA (0.67) MAOACYP3A4MAOBLMNAPTGS1
SCHEMBL6624452 0.85 MAOA (0.61) MAOACYP3A4MAOBLMNAPTGS1
SCHEMBL3171586 0.85 MAOA (0.69) MAOACYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US claimed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD MAOA 1717/4885CYP3A4 207/4885CYP2D6 295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.