Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | GFRA3 | O60609 | 2/20 | 0.41 |
| ▸ | GFRA2 | O00451 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997543 | 0.89 | TGM2 (0.42) | TGM2GFRA3GFRA2EGFRERBB2 | |
| SCHEMBL30357040 | 0.89 | TGM2 (0.42) | TGM2GFRA3GFRA2EGFRERBB2 | |
| SCHEMBL28996940 | 0.89 | TGM2 (0.44) | TGM2FFAR1KCNA5MTNR1A | |
| SCHEMBL28997043 | 0.89 | TGM2 (0.50) | TGM2FFAR1EGFRMTNR1A | |
| SCHEMBL28997018 | 0.88 | ALDH1A1 (0.43) | TGM2GFRA3GFRA2EGFRRET | |
| SCHEMBL29370569 | 0.88 | ALDH1A1 (0.43) | TGM2GFRA3GFRA2EGFRRET | |
| SCHEMBL28997004 | 0.88 | TGM2 (0.41) | TGM2GFRA3GFRA2EGFRBTK | |
| SCHEMBL29366852 | 0.88 | TGM2 (0.41) | TGM2GFRA3GFRA2EGFRBTK | |
| SCHEMBL29370151 | 0.87 | EGFR (0.40) | TGM2GFRA3GFRA2EGFRBTK | |
| SCHEMBL28997590 | 0.87 | EGFR (0.40) | TGM2GFRA3GFRA2EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | disclosed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |