Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394473 | 0.87 | LCK (0.47) | RXFP1LCKNPC1RAB9AMEN1 | |
| SCHEMBL30258903 | 0.86 | KMT2A (0.47) | SORT1HDAC1GRM5NPC1RAB9A | |
| SCHEMBL3427901 | 0.85 | MAPK8 (0.47) | SORT1MAPK8LCKNPC1RAB9A | |
| SCHEMBL29510654 | 0.84 | ALDH1A1 (0.51) | SORT1RXFP1GRM5LCKMEN1 | |
| SCHEMBL1712579 | 0.84 | ALDH1A1 (0.51) | SORT1RXFP1GRM5LCKMEN1 | |
| SCHEMBL29497169 | 0.83 | GRM5 (0.48) | GRM5LCKNPC1RAB9AMEN1 | |
| SCHEMBL1192089 | 0.83 | GRM5 (0.48) | GRM5LCKNPC1RAB9AMEN1 | |
| SCHEMBL16874236 | 0.83 | MAPK8 (0.42) | SORT1MAPK8LCKNPC1RAB9A | |
| SCHEMBL29607855 | 0.83 | MAPK8 (0.42) | SORT1MAPK8LCKNPC1RAB9A | |
| SCHEMBL22842960 | 0.83 | SORT1 (0.48) | SORT1RXFP1GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |