Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30284999 | 1.00 | GRM5 (0.48) | GRM5ALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30284986 | 0.80 | GRM5 (0.52) | GRM5ALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL17992350 | 0.80 | GRM5 (0.52) | GRM5ALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19512898 | 0.78 | GRM5 (0.53) | GRM5KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30285019 | 0.77 | KMT2A (0.46) | ALOX15KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL1169382 | 0.77 | ALDH1A1 (0.54) | ALOX15KDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL259393 | 0.76 | NPC1 (0.67) | KDM4EALDH1A1CA1CA2CA5A | |
| SCHEMBL28997458 | 0.76 | HPGD (0.48) | KDM4EALDH1A1DRD2HTTSMN1; SMN2 | |
| SCHEMBL19512975 | 0.75 | SLC6A3 (0.52) | GRM5ALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL17992351 | 0.75 | KDM4E (0.49) | GRM5ALOX15KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |