Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 15/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 15/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 11/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998741 | 0.87 | RAB9A (0.50) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL28998201 | 0.86 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL28998727 | 0.83 | GAA (0.37) | KCNQ3KCNQ2KCNE1KCNQ1SMN1; SMN2 | |
| SCHEMBL28998183 | 0.82 | JAK2 (0.34) | RAB9ASMN1; SMN2BACE1MEN1KMT2A | |
| SCHEMBL28998221 | 0.79 | KMT2A (0.42) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL24867499 | 0.75 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1RAB9A | |
| SCHEMBL28998733 | 0.74 | BACE1 (0.39) | BACE1 | |
| SCHEMBL28998215 | 0.74 | — | — | |
| SCHEMBL28998794 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28998795 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |