Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998220 | 0.90 | MAPT (0.36) | KDM4ESMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL28998195 | 0.89 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL28998178 | 0.89 | BCL2 (0.41) | MAPKAPK2 | |
| SCHEMBL28998174 | 0.88 | NPC1 (0.34) | KDM4ESMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL28998172 | 0.87 | SMN1; SMN2 (0.42) | KDM4ESMN1; SMN2TSHRALDH1A1MAPT | |
| SCHEMBL28998224 | 0.86 | CYP1A2 (0.38) | SMN1; SMN2ALDH1A1TP53MAPTRAB9A | |
| SCHEMBL28998796 | 0.85 | PTPN1 (0.51) | KDM4ESMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL28998180 | 0.84 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL28998165 | 0.84 | L3MBTL1 (0.39) | KDM4ESMN1; SMN2TSHRTP53MAPT | |
| SCHEMBL28998187 | 0.83 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |