Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228003 | 1.00 | GRM5 (0.32) | GRM5NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL30242765 | 0.87 | NPC1 (0.34) | GRM5NPC1RAB9A | |
| SCHEMBL25624480 | 0.87 | NPC1 (0.34) | GRM5NPC1RAB9A | |
| SCHEMBL24014348 | 0.86 | GRM5 (0.32) | GRM5 | |
| SCHEMBL28998941 | 0.85 | MAP4K3 (0.32) | GRM5NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL30228243 | 0.85 | MAP4K3 (0.32) | GRM5NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL25108582 | 0.79 | GRM5 (0.38) | GRM5SYK | |
| SCHEMBL28982116 | 0.78 | — | — | |
| SCHEMBL24013899 | 0.76 | MAPK14 (0.30) | — | |
| SCHEMBL25624485 | 0.75 | RIPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916196-A | Heteroaromatic macrocyclic ether chemotherapeutic agents | 纽威伦特公司 | 2023-04-04 | — | — | CN | disclosed |