Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881883 | 1.00 | SOS1 (0.36) | SOS1TSHRNOTUMCA1CA2 | |
| SCHEMBL30762200 | 0.82 | TSHR (0.34) | TSHRNOTUMCA1CA2BCAT1 | |
| SCHEMBL29278102 | 0.82 | TSHR (0.34) | TSHRNOTUMCA1CA2BCAT1 | |
| SCHEMBL9003991 | 0.82 | GABRA1 (0.40) | TSHRNOTUMCA1CA2ALDH1A1 | |
| SCHEMBL8849052 | 0.81 | TRPV4 (0.36) | EGLN2CYP11B1CYP11B2TRPV4 | |
| SCHEMBL3974692 | 0.80 | TSHR (0.44) | TSHRCA1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL1533157 | 0.79 | TSHR (0.46) | TSHRNOTUMCA1CA2BCAT1 | |
| SCHEMBL24681944 | 0.79 | CYP1A2 (0.40) | TSHRNOTUMBCAT1ALDH1A1L3MBTL1 | |
| SCHEMBL16951161 | 0.79 | NOTUM (0.35) | TSHRNOTUMCA1CA2BCAT1 | |
| SCHEMBL16950500 | 0.79 | NOTUM (0.38) | SOS1TSHRNOTUMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-2427801-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | Hewlett-Packard Development Company, L.P. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128969-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |