⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348291 | 0.81 | — | — | |
| SCHEMBL11594291 | 0.81 | — | — | |
| SCHEMBL157610 | 0.81 | — | — | |
| SCHEMBL893060 | 0.78 | CHRNA4 (0.41) | — | |
| SCHEMBL19064429 | 0.76 | CHRNA4 (0.36) | — | |
| SCHEMBL3940897 | 0.76 | CHRNA4 (0.40) | — | |
| SCHEMBL19064369 | 0.76 | NPC1 (0.51) | — | |
| SCHEMBL656888 | 0.76 | ATM (0.43) | — | |
| SCHEMBL29348788 | 0.76 | NPC1 (0.53) | — | |
| Hydrochloric Acid SCHEMBL3938535 | 0.75 | CHRNA4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420550-B | N-hydroxyamide compound containing dihydroquinazolinone, and preparation method and application thereof | 亳州学院 | 2026-05-22 | — | — | CN | disclosed |
| CN-116496179-B | HDAC6 inhibitor containing chalcone structure, and preparation method and application thereof | 合肥工业大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118420550-A | N-hydroxyamide compound containing dihydroquinazolinone, and preparation method and application thereof | 亳州学院 | 2024-08-02 | — | — | CN | disclosed |
| US-11739064-B2 | HDAC inhibitors and therapeutic methods using the same | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-08-29 | — | — | US | disclosed |
| CN-116496179-A | HDAC6 inhibitor containing chalcone structure, and preparation method and application thereof | 合肥工业大学 | 2023-07-28 | — | — | CN | disclosed |
| EP-3468957-B1 | CRYSTALLINE FORM OF (R)-4-(5-(CYCLOPROPYLETHYNYL)ISOXAZOL-3-YL)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)BUTANAMIDE AS AN ANTIBACTERIAL AGENT | NOVARTIS AG (CH) | 2020-08-26 | — | — | EP | disclosed |
| US-10071973-B2 | Crystalline isoxazole hydroxamic acid compounds | NOVARTIS AG (CH) | 2018-09-11 | — | — | US | disclosed |
| CN-107001295-A | Isoxazole hydroxamic acid compounds as lpxc inhibitors | 诺华股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-107001295-A | Isoxazole hydroxamic acid compounds as lpxc inhibitors | 诺华股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |