⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289997 | 0.81 | — | — | |
| SCHEMBL755315 | 0.79 | — | — | |
| SCHEMBL157610 | 0.79 | — | — | |
| SCHEMBL11594291 | 0.79 | — | — | |
| SCHEMBL893060 | 0.76 | CHRNA4 (0.41) | — | |
| SCHEMBL11299790 | 0.76 | CHRNA4 (0.37) | — | |
| SCHEMBL28273457 | 0.75 | CHRNA4 (0.44) | — | |
| SCHEMBL19064369 | 0.75 | NPC1 (0.51) | — | |
| SCHEMBL656888 | 0.75 | ATM (0.43) | — | |
| SCHEMBL19064429 | 0.75 | CHRNA4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |