Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009348 | 0.79 | DRD1 (0.39) | SCN9AALDH1A1MAPT | |
| SCHEMBL29149347 | 0.79 | DRD1 (0.39) | SCN9AALDH1A1MAPT | |
| SCHEMBL6365979 | 0.78 | ALDH1A1 (0.49) | TDP1ALDH1A1MAPTRAB9A | |
| SCHEMBL3487966 | 0.78 | KDM4A (0.48) | SCN9AALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL29462665 | 0.77 | ATM (0.63) | ATMTDP1ALDH1A1MAPTPDE7A | |
| SCHEMBL26108533 | 0.76 | SCN9A (0.42) | SCN9AALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL24121175 | 0.75 | ALDH1A1 (0.42) | SCN9AALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL30362932 | 0.73 | ATM (0.44) | ATMTDP1SCN9AALDH1A1MAPT | |
| SCHEMBL26106670 | 0.73 | HTR2A (0.42) | ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL22636731 | 0.73 | GRM5 (0.41) | TDP1SCN9AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075512-A | Heterocyclic compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-05 | — | — | CN | disclosed |