Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009348 | 1.00 | DRD1 (0.39) | DRD1SCN9ASOS1ALDH1A1HTT | |
| SCHEMBL24749528 | 0.80 | DRD1 (0.42) | DRD1SCN9ASOS1ALDH1A1MAPT | |
| SCHEMBL28999948 | 0.79 | ATM (0.44) | SCN9AALDH1A1MAPT | |
| SCHEMBL29938948 | 0.79 | SCN4A (0.42) | SCN9ASOS1ALDH1A1HTTMAPT | |
| SCHEMBL29149455 | 0.75 | MAPT (0.50) | SOS1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL29938158 | 0.75 | MAPT (0.50) | SOS1ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL31009494 | 0.71 | ALDH1A1 (0.47) | SOS1ALDH1A1HTT | |
| SCHEMBL6365979 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MAPT | |
| SCHEMBL30768319 | 0.69 | SOS1 (0.42) | SOS1ALDH1A1HTT | |
| SCHEMBL22636731 | 0.68 | GRM5 (0.41) | SCN9AALDH1A1MAPTKDM4EAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |