Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422636 | 0.80 | TDO2 (0.36) | PSMB5TDO2JAK2JAK1TYK2 | |
| SCHEMBL2940858 | 0.79 | PSMB5 (0.38) | PSMB5TDO2ALDH1A1TP53CYP3A4 | |
| SCHEMBL28328037 | 0.76 | PSMB5 (0.49) | PSMB5TDO2ALDH1A1TP53CYP3A4 | |
| SCHEMBL532225 | 0.76 | ALDH1A1 (0.33) | PSMB5TDO2ALDH1A1TP53CYP3A4 | |
| SCHEMBL9167795 | 0.75 | PSMB5 (0.46) | PSMB5TDO2JAK2JAK1TYK2 | |
| SCHEMBL3400335 | 0.74 | TDO2 (0.37) | PSMB5TDO2JAK2JAK1TYK2 | |
| Hydrochloric Acid SCHEMBL28329189 | 0.74 | PSMB5 (0.47) | PSMB5TDO2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL28510609 | 0.74 | PSMB5 (0.47) | PSMB5TDO2ALDH1A1TP53CYP3A4 | |
| SCHEMBL532888 | 0.73 | CYP3A4 (0.34) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL24521805 | 0.72 | TDP1 (0.42) | PSMB5TDO2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115612438-B | Heat-conducting polyurethane structural adhesive with improved high-temperature retention rate and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2023-05-09 | — | — | CN | disclosed |