Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 17/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380155 | 1.00 | PARP1 (0.51) | PARP1ALDH1A1PARP2KDM4EMAPT | |
| SCHEMBL10868710 | 0.86 | ALDH1A1 (0.58) | PARP1ALDH1A1PARP2PARP3 | |
| SCHEMBL818929 | 0.83 | ALDH1A1 (0.70) | PARP1ALDH1A1PARP2MAPTPARP3 | |
| SCHEMBL10555620 | 0.83 | ALDH1A1 (0.70) | PARP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29611021 | 0.83 | ALDH1A1 (0.70) | PARP1ALDH1A1PARP2MAPTPARP3 | |
| SCHEMBL2624160 | 0.82 | PARP1 (0.51) | PARP1ALDH1A1PARP2 | |
| SCHEMBL28274572 | 0.82 | ACHE (0.57) | PARP1ALDH1A1PARP2KDM4EMAPT | |
| SCHEMBL26523348 | 0.81 | ALDH1A1 (0.49) | PARP1ALDH1A1KDM4EMAPT | |
| SCHEMBL2606618 | 0.80 | PARP1 (0.56) | PARP1ALDH1A1PARP2 | |
| SCHEMBL8411208 | 0.79 | PARP1 (0.54) | PARP1ALDH1A1PARP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134026-A | Triazole derivatives and their use as tankyrase inhibitors | 奥斯陆大学国家医院 | 2023-05-16 | — | — | CN | disclosed |