⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260334 | 0.79 | DRD1 (0.30) | — | |
| SCHEMBL28816601 | 0.79 | RORC (0.31) | — | |
| SCHEMBL608168 | 0.79 | RORC (0.31) | — | |
| SCHEMBL28048028 | 0.79 | — | — | |
| SCHEMBL7482415 | 0.76 | — | — | |
| SCHEMBL9532661 | 0.76 | — | — | |
| SCHEMBL1407804 | 0.74 | — | — | |
| SCHEMBL3326062 | 0.73 | SRC (0.30) | — | |
| SCHEMBL29118033 | 0.72 | — | — | |
| SCHEMBL8217121 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115737651-A | Triazine derivatives as interferon-gamma inhibitors | 格林威治大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115737651-A | Triazine derivatives as interferon-gamma inhibitors | 格林威治大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-107921046-B | Triazine derivatives as interferon-gamma inhibitors | 格林威治大学 | 2022-10-14 | — | — | CN | disclosed |