⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606006 | 0.87 | LMNA (0.34) | — | |
| SCHEMBL3079149 | 0.87 | — | — | |
| SCHEMBL80520 | 0.81 | KIF11 (0.31) | — | |
| SCHEMBL9325480 | 0.79 | — | — | |
| SCHEMBL1008473 | 0.78 | — | — | |
| SCHEMBL9532550 | 0.78 | — | — | |
| SCHEMBL15271374 | 0.78 | — | — | |
| SCHEMBL7460444 | 0.78 | — | — | |
| SCHEMBL9528791 | 0.78 | — | — | |
| SCHEMBL10466971 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | UNIVERSITY OF GREENWICH (GB) | 2020-03-03 | — | — | US | claimed |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIVERSITY OF GREENWICH (GB) | 2018-06-21 | — | — | US | claimed |
| EP-2295429-A1 | 3-((hetero)aryl)-indazoles as Liver X receptor (LXR) and Th-1 inhibitors for the treatment of cardiovascular diseases | Wyeth LLC (US) | 2011-03-16 | — | — | EP | claimed |
| US-7592363-B2 | Indazoles | WYETH (US) | 2009-09-22 | — | — | US | claimed |
| EP-1773781-A2 | INDAZOLES USEFUL IN TREATING CARDIOVASCULAR DISEASES | Wyeth (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006017384-A2 | INDAZOLES USEFUL IN TREATING CARDIOVASCULAR DISEASES | WYETH (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060030612-A1 | Indazoles useful in treating cardiovascular diseases | WYETH (US) | 2006-02-09 | — | — | US | claimed |
| EP-0176956-B1 | Diaryl derivatives | BYK GULDEN LOMBERG CHEM FAB (DE) | 1994-06-15 | — | — | EP | claimed |
| EP-0393074-A1 | NEW PYRROLIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1990-10-24 | — | — | EP | claimed |
| EP-0336132-A1 | 1-Phenylpropyl compounds | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-10-11 | — | — | EP | claimed |
| WO-1989008644-A1 | NEW 1-PHENYLPROPYL COMPOUNDS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-09-21 | — | — | WO | claimed |
| WO-1989003824-A1 | NEW PYRROLIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-05-05 | — | — | WO | claimed |
| EP-0314038-A1 | Pyrrolidines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1989-05-03 | — | — | EP | claimed |
| WO-1988001266-A1 | NEW PIPERIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-02-25 | — | — | WO | claimed |
| EP-0244595-A2 | Dihydropyridine derivatives, process for their preparation and their use as pharmaceutical compounds | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1987-11-11 | — | — | EP | claimed |
| EP-0176956-A2 | Diaryl derivatives | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1986-04-09 | — | — | EP | claimed |
| US-4043791-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | claimed |
| EP-3307273-B1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIV GREENWICH (GB) | 2020-12-09 | — | — | EP | disclosed |
| EP-0010420-A1 | Pyridyl-substituted thiazolidine and 1,3-thiazine derivatives, processes for their preparation, agricultural compositions containing said derivatives and methods for regulating plant growth and protecting plants from fungi | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4043791-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |