Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538411 | 0.75 | CA12 (0.44) | TTRRAB9AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11223890 | 0.75 | ACMSD (0.47) | DHODHACMSDPOLBNPC1RAB9A | |
| SCHEMBL11230003 | 0.75 | ACMSD (0.54) | DHODHACMSDPOLBNPC1RAB9A | |
| SCHEMBL10727565 | 0.74 | DHODH (0.46) | DHODHNPC1RAB9ADHFRALKBH5 | |
| SCHEMBL29697829 | 0.74 | DHODH (0.42) | DHODHACMSDNPC1RAB9ADHFR | |
| SCHEMBL25620982 | 0.73 | ACMSD (0.41) | ACMSDPOLBNPC1RAB9ACES2 | |
| SCHEMBL26632144 | 0.73 | ACMSD (0.53) | DHODHACMSDTTRNPC1RAB9A | |
| SCHEMBL28566012 | 0.72 | CA12 (0.59) | ACMSDNPC1RAB9ACES2CES1 | |
| SCHEMBL4428959 | 0.71 | ACMSD (0.55) | DHODHACMSDTTRNPC1RAB9A | |
| SCHEMBL28119663 | 0.71 | MYC (0.46) | DHODHACMSDNPC1RAB9ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349726-B | 2,2' -difluoro-4, 4', 5' -biphenyl tetracarboxylic dianhydride monomer, and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | claimed |