Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127505 | 0.79 | RPA1 (0.54) | NPC1RAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL26597141 | 0.76 | RAB9A (0.61) | NPC1RAB9AALDH1A1ATML3MBTL1 | |
| SCHEMBL29697841 | 0.75 | GAA (0.46) | DHODHNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL24072982 | 0.74 | KDM4E (0.64) | DHODHALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL29002234 | 0.74 | DHODH (0.45) | DHODHNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL29697849 | 0.74 | FBP1 (0.51) | DHODHALDH1A1KMT2ARPA1MCL1 | |
| SCHEMBL27813582 | 0.73 | ALDH1A1 (0.69) | DHODHALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL10727565 | 0.73 | DHODH (0.46) | DHODHNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL26597135 | 0.72 | GRIA2 (0.46) | DHODHATMKMT2ADHFRALKBH5 | |
| SCHEMBL11736111 | 0.72 | MAP2 (0.45) | DHODHALDH1A1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022134837-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | 深圳市祥根生物医药有限公司 | 2022-06-30 | — | — | WO | disclosed |