SCHEMBL2900253

SCHEMBL2900253

C[SiH](C)OCCN=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3466411 0.86
SCHEMBL3465997 0.85
SCHEMBL3467083 0.83 TRPA1 (0.31)
SCHEMBL17272683 0.83 TRPA1 (0.31)
SCHEMBL441179 0.77
SCHEMBL6538814 0.76
SCHEMBL14694029 0.76
SCHEMBL728592 0.76
SCHEMBL165066 0.72
SCHEMBL108059 0.71 NAAA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425695-A Curable composition and cured product 综研化学株式会社 2024-01-19 CN disclosed
CN-115335452-A Curable composition and cured product 综研化学株式会社 2022-11-11 CN disclosed
US-10725379-B2 Polymide precursor resin composition HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2020-07-28 US disclosed
CN-105829968-B Resin composition containing polyimide precursor and method for producing cured film using same 日立化成杜邦微系统股份有限公司 2020-03-27 CN disclosed
US-20150337116-A1 POLYMIDE PRECURSOR RESIN COMPOSITION HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2015-11-26 US disclosed
US-8304569-B2 Method for producing isocyanate-terminated siloxanes WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
US-20100286426-A1 METHOD FOR PRODUCING ISOCYANATE-TERMINATED SILOXANES WACKER CHEMIE AG (DE) 2010-11-11 US disclosed
US-20100047589-A1 LAMINATES COMPRISING THERMOPLASTIC POLYSILOXANE-UREA COPOLYMERS WACKER CHEMIE AG (DE) 2010-02-25 US disclosed
US-7368586-B2 Organosilicon compounds with a masked isocyanate group WACKER CHEMIE AG (DE) 2008-05-06 US disclosed
EP-1771457-B1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP WACKER CHEMIE AG (DE) 2007-12-12 EP disclosed
US-20070123644-A1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP WACKER CHEMIE AG (DE) 2007-05-31 US disclosed
EP-1771457-A1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP Wacker Chemie AG (DE) 2007-04-11 EP disclosed
US-20060204765-A1 Laminated glass with polysiloxane-urea copolymer WACKER-CHEMIE GMBH (DE) 2006-09-14 US disclosed
WO-2006012957-A1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP WACKER CHEMIE AG (DE) 2006-02-09 WO disclosed
US-4736046-A CROSSLINKERS THE DOW CHEMICAL COMPANY (US) 1988-04-05 US disclosed