Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003294 | 1.00 | ATR (0.40) | ATRRXRARXRBRXRGATM | |
| SCHEMBL29003348 | 1.00 | ATR (0.40) | ATRRXRARXRBRXRGATM | |
| SCHEMBL29470593 | 0.89 | RXRA (0.45) | ATRRXRARXRBRXRGCYP4F2 | |
| SCHEMBL29003191 | 0.88 | RXRA (0.39) | ATRRXRARXRBRXRGATM | |
| SCHEMBL29470606 | 0.88 | RXRA (0.39) | ATRRXRARXRBRXRGATM | |
| SCHEMBL30424835 | 0.87 | ATR (0.39) | ATRRXRARXRBRXRGRET | |
| SCHEMBL29003212 | 0.87 | ATR (0.39) | ATRRXRARXRBRXRGRET | |
| SCHEMBL29003209 | 0.87 | ATR (0.39) | ATRRXRARXRBRXRGRET | |
| SCHEMBL29003393 | 0.87 | ATR (0.39) | ATRRXRARXRBRXRGRET | |
| SCHEMBL20699398 | 0.86 | RXRA (0.41) | ATRRXRARXRBRXRGCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |