Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30362248 | 0.82 | PTGDR2 (0.38) | AAK1NAMPTUSP30PRMT5WDR77 | |
| SCHEMBL25251320 | 0.82 | PTGDR2 (0.38) | AAK1NAMPTUSP30PRMT5WDR77 | |
| SCHEMBL30362262 | 0.81 | NAMPT (0.35) | AAK1NAMPTUSP30PRMT5WDR77 | |
| SCHEMBL25350925 | 0.81 | NAMPT (0.35) | AAK1NAMPTUSP30PRMT5WDR77 | |
| SCHEMBL25254861 | 0.80 | MAPKAPK2 (0.36) | AAK1NAMPTPRMT5WDR77MAPKAPK2 | |
| SCHEMBL30362298 | 0.80 | MAPKAPK2 (0.36) | AAK1NAMPTPRMT5WDR77MAPKAPK2 | |
| SCHEMBL25297826 | 0.79 | AR (0.39) | AAK1NAMPTMAPKAPK2 | |
| SCHEMBL30362342 | 0.79 | AR (0.39) | AAK1NAMPTMAPKAPK2 | |
| SCHEMBL24117255 | 0.79 | HDAC3 (0.57) | FFAR1AAK1NAMPTUSP30PRMT5 | |
| SCHEMBL1255934 | 0.77 | AAK1 (0.54) | AAK1NAMPTPRMT5WDR77DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989227-A | Imidazole-pyrazole derivatives having antibacterial properties | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |