Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342202 | 0.88 | SYK (0.53) | CTSKTP53PPARACTSSCTSL | |
| SCHEMBL30342183 | 0.87 | CTSK (0.48) | CTSKTP53SLC6A9PPARASLC6A5 | |
| SCHEMBL30345149 | 0.85 | TP53 (0.50) | CTSKTP53SLC6A9PPARASLC6A5 | |
| Hydrochloric Acid SCHEMBL29005181 | 0.84 | TP53 (0.49) | CTSKTP53SLC6A9PPARASLC6A5 | |
| SCHEMBL2011885 | 0.79 | SLC6A9 (0.70) | TP53SLC6A9SLC6A5HTTSMN1; SMN2 | |
| SCHEMBL7329157 | 0.73 | CTSK (0.58) | CTSKPPARACTSSCTSLCTSB | |
| SCHEMBL1191975 | 0.73 | CTSK (0.58) | CTSKPPARACTSSCTSLCTSB | |
| SCHEMBL24130315 | 0.72 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL24130316 | 0.72 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| Benzyl Benzoate SCHEMBL30345166 | 0.72 | KMT2A (0.44) | CTSKTP53SLC6A9SLC6A5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |