Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342225 | 1.00 | L3MBTL1 (0.43) | L3MBTL1MLYCDNNMTSMN1; SMN2SCN9A | |
| SCHEMBL15350216 | 0.83 | L3MBTL1 (0.47) | L3MBTL1NNMTSMN1; SMN2IL1BCNR2 | |
| SCHEMBL2712958 | 0.80 | CNR2 (0.42) | L3MBTL1MLYCDSCN9ACNR2POLB | |
| SCHEMBL29005276 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MLYCDSCN9ACNR2POLB | |
| SCHEMBL30342136 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MLYCDSCN9ACNR2POLB | |
| SCHEMBL2713528 | 0.78 | L3MBTL1 (0.63) | L3MBTL1MLYCDSCN9APOLBMAPK1 | |
| SCHEMBL31191212 | 0.78 | CNR2 (0.37) | L3MBTL1MLYCDSCN9ACNR2HCRTR1 | |
| SCHEMBL458005 | 0.78 | L3MBTL1 (0.58) | L3MBTL1NNMTSMN1; SMN2SCN9AIL1B | |
| SCHEMBL29990185 | 0.76 | CNR2 (0.45) | MLYCDSCN9ACNR2HCRTR1HCRTR2 | |
| SCHEMBL15350909 | 0.76 | CNR2 (0.40) | L3MBTL1MLYCDCNR2GABRA1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |