Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 6/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005276 | 1.00 | L3MBTL1 (0.43) | L3MBTL1SIRT6CNR2BACE1BACE2 | |
| SCHEMBL16601358 | 0.81 | SIRT6 (0.59) | SIRT6OXTRAVPR1A | |
| SCHEMBL31132803 | 0.80 | L3MBTL1 (0.48) | L3MBTL1SIRT6CNR2BACE1BACE2 | |
| SCHEMBL2108636 | 0.80 | L3MBTL1 (0.48) | L3MBTL1SIRT6CNR2BACE1BACE2 | |
| SCHEMBL24774974 | 0.80 | MLYCD (0.40) | SIRT6MLYCDSCN9AOXTRAVPR1A | |
| SCHEMBL30108431 | 0.80 | MLYCD (0.40) | SIRT6MLYCDSCN9AOXTRAVPR1A | |
| SCHEMBL2713528 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MLYCDPOLBMAPK1SCN9A | |
| SCHEMBL31191212 | 0.80 | CNR2 (0.37) | L3MBTL1CNR2MLYCDSCN9A | |
| SCHEMBL29005252 | 0.80 | L3MBTL1 (0.43) | L3MBTL1CNR2MLYCDPOLBMAPK1 | |
| SCHEMBL30342225 | 0.80 | L3MBTL1 (0.43) | L3MBTL1CNR2MLYCDPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168393-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-04-26 | — | — | EP | disclosed |