SCHEMBL29005451

SCHEMBL29005451

CCOC(=O)c1nn(-c2ccc(Cl)cc2)c2cccc(Oc3ccc(F)cc3)c2c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
APP P05067 2/20 0.46
MEN1 O00255 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CASP1 P29466 1/20 0.46
ALDH1A1 P00352 3/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
NPBWR1 P48145 1/20 0.44
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ELANE P08246 2/20 0.42
P2RY12 Q9H244 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26074802 0.86 KMT2A (0.46) KMT2AMAPTMEN1NPSR1KDM4E
SCHEMBL30310934 0.86 KMT2A (0.46) KMT2AMAPTMEN1NPSR1KDM4E
SCHEMBL24047230 0.85 MAPT (0.51) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL30212133 0.85 MAPT (0.51) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL9338844 0.77 NPBWR1 (0.44) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL9495320 0.77 SLC5A1 (0.47) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL9338745 0.77 SLC5A1 (0.48) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL9401238 0.76 MAPT (0.43) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL8638653 0.75 KMT2A (0.43) KMT2AMAPTAPPMEN1L3MBTL1
SCHEMBL26074829 0.74 SLC5A1 (0.47) KMT2AMAPTAPPMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115802892-A Herbicidal cinnoline derivatives 先正达农作物保护股份公司 2023-03-14 CN disclosed