Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401238 | 0.90 | MAPT (0.43) | KMT2AMEN1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8641122 | 0.88 | RORC (0.41) | RORCRXFP1TDP1NR3C1RARG | |
| SCHEMBL8637313 | 0.87 | RORC (0.52) | KMT2AMEN1KDM4EMAPTL3MBTL1 | |
| SCHEMBL8830130 | 0.82 | CYP1A2 (0.41) | KMT2AKDM4EMAPTRORCNPSR1 | |
| SCHEMBL8636437 | 0.80 | MAPK1 (0.41) | KMT2AMEN1KDM4EMAPTRORC | |
| SCHEMBL30310934 | 0.80 | KMT2A (0.46) | KMT2AMEN1KDM4EMAPTRORC | |
| SCHEMBL26074802 | 0.80 | KMT2A (0.46) | KMT2AMEN1KDM4EMAPTRORC | |
| SCHEMBL124027 | 0.79 | MALT1 (0.41) | KMT2AMAPTPOLBRORCTP53 | |
| SCHEMBL8641097 | 0.79 | RORC (0.49) | KMT2AMEN1KDM4EMAPTL3MBTL1 | |
| SCHEMBL28971929 | 0.79 | CCR1 (0.39) | KMT2AMEN1RORCALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519140-B1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acids, esters and salts thereof, and intermediates used in this method | HYBRINOVA (FR) | 1998-07-29 | — | — | EP | disclosed |
| US-5696055-A | USED IN INDUCING MALE STERILITY OR PRODUCING HYBRID SEEDS IN A GRAMINEOUS PLANT | HYBRINOVA S.A. (FR) | 1997-12-09 | — | — | US | disclosed |
| EP-0363236-B1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1994-12-07 | — | — | EP | disclosed |
| US-5332716-A | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | E.I. DU PONT DE NEMOURS AND COMPANY | 1994-07-26 | — | — | US | disclosed |
| US-5304672-A | Intermediates for pollen suppressants | ORSAN (FR) | 1994-04-19 | — | — | US | disclosed |
| EP-0530064-A1 | Pollen suppressant for Liliopsida plants comprising a 5-oxy-substituted cinnoline | HYBRINOVA (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0530063-A1 | Pollen suppressant for dicotyledon plants comprising a 5-oxy-substituted cinnoline | ORSAN (FR) | 1993-03-03 | — | — | EP | disclosed |
| US-5183891-A | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | ORSAN (FR) | 1993-02-02 | — | — | US | disclosed |
| EP-0519140-A1 | Method for the preparation of substituted 1,4-dihydro-4-oxo-cinnoline-3-carboxylic acid, esters and salts thereof, and intermediates used in their preparation | HYBRINOVA (FR) | 1992-12-23 | — | — | EP | disclosed |
| US-5129940-A | Antifertility agents for Liliopsida | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |
| US-5129939-A | Antifertility agents | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |
| EP-0363236-A1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1990-04-11 | — | — | EP | disclosed |