Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30285715 | 1.00 | ROCK1 (0.47) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25371664 | 0.88 | TDO2 (0.51) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25374104 | 0.88 | MEN1 (0.46) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25372501 | 0.84 | ROCK1 (0.43) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25371947 | 0.84 | ABCG2 (0.44) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25371942 | 0.84 | GRM4 (0.44) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25371811 | 0.84 | GRM4 (0.44) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25373733 | 0.83 | GRM4 (0.46) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL29005506 | 0.82 | MEN1 (0.67) | ROCK1MEN1KMT2AALOX12MAPT | |
| SCHEMBL25371674 | 0.81 | NPC1 (0.42) | ROCK1MEN1KMT2AALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |