Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | BCR | P11274 | 3/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371875 | 0.84 | KMT2A (0.60) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25371736 | 0.83 | ROCK1 (0.52) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL29005456 | 0.82 | ROCK1 (0.47) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL30285715 | 0.82 | ROCK1 (0.47) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25371959 | 0.81 | EPAS1 (0.52) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL26310347 | 0.81 | KMT2A (0.62) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25371617 | 0.80 | ROCK1 (0.52) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25371664 | 0.78 | TDO2 (0.51) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25374104 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAPTEGFRROCK1 | |
| SCHEMBL25375898 | 0.78 | EGFR (0.47) | MEN1KMT2AMAPTEGFRROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |