Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.55 |
| ▸ | KCNJ5 | P48544 | 5/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403121 | 0.78 | ALDH1A1 (0.50) | ANO1 | |
| SCHEMBL26186573 | 0.76 | P2RX4 (0.60) | ANO1KCNJ5KCNJ3P2RX4KCNJ6 | |
| SCHEMBL21198480 | 0.73 | ANO1 (0.71) | ANO1KCNJ5KCNJ3KCNJ6 | |
| SCHEMBL31306626 | 0.73 | ANO1 (0.71) | ANO1KCNJ5KCNJ3KCNJ6 | |
| SCHEMBL30368230 | 0.71 | JAK2 (0.62) | ANO1KCNJ5KCNJ3P2RX4KCNJ6 | |
| SCHEMBL30502369 | 0.71 | KCNJ5 (0.68) | ANO1KCNJ5KCNJ3KCNJ6CLK2 | |
| SCHEMBL21198045 | 0.71 | ANO1 (1.00) | ANO1 | |
| SCHEMBL31306145 | 0.71 | ANO1 (1.00) | ANO1 | |
| SCHEMBL25902500 | 0.71 | ANO1 (0.51) | ANO1KCNJ5KCNJ3P2RX4KCNJ6 | |
| SCHEMBL31306581 | 0.70 | ANO1 (0.71) | ANO1KCNJ5KCNJ3KCNJ6RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996911-A | Substituted N-phenylacetamides having P2X4 receptor antagonistic activity | 拜耳公司 | 2023-04-21 | — | — | CN | disclosed |