Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 11/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30403105 | 0.79 | ANO1 (0.49) | ANO1ROCK2 | |
| SCHEMBL30402922 | 0.78 | ANO1 (0.61) | ALDH1A1ANO1 | |
| SCHEMBL29005472 | 0.78 | ANO1 (0.55) | ANO1 | |
| SCHEMBL25370426 | 0.77 | P2RX4 (0.62) | ALDH1A1ANO1ROCK2P2RX7 | |
| SCHEMBL30402844 | 0.75 | ANO1 (0.61) | ANO1ROCK2P2RX7 | |
| SCHEMBL30368260 | 0.75 | ANO1 (0.53) | ANO1ROCK2P2RX7POLB | |
| SCHEMBL30285786 | 0.74 | P2RX4 (0.60) | ANO1ROCK2P2RX7 | |
| SCHEMBL26186489 | 0.74 | P2RX4 (0.60) | ANO1ROCK2P2RX7 | |
| SCHEMBL26186535 | 0.73 | P2RX4 (0.61) | ANO1ROCK2 | |
| SCHEMBL12824945 | 0.73 | MEN1 (0.54) | ALDH1A1LMNAMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115989218-A | Use of N-phenylacetamides having P2X4 receptor antagonistic activity for the treatment of certain eye diseases | 拜耳公司 | 2023-04-18 | — | — | CN | disclosed |