Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513052 | 0.96 | MAP3K5 (0.37) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL29363550 | 0.96 | MAP3K5 (0.37) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL29198503 | 0.82 | TSHR (0.41) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL30182911 | 0.79 | MAPT (0.38) | ALDH1A1POLBLMNAKMT2AGAA | |
| SCHEMBL24268660 | 0.78 | MAP3K5 (0.39) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL1114562 | 0.78 | DGAT2 (0.38) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL14538892 | 0.78 | GAA (0.45) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL20764905 | 0.78 | GAA (0.42) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL29092783 | 0.78 | MAP3K5 (0.39) | TSHRKDM4EALDH1A1POLBLMNA | |
| SCHEMBL29879089 | 0.78 | MAP3K5 (0.39) | TSHRKDM4EALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |