SCHEMBL29006167

SCHEMBL29006167

Cc1ccc(C(O)C[Se]c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.52
CA7 P43166 3/20 0.50
MAOB P27338 1/20 0.50
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
LMNA P02545 2/20 0.42
CA4 P22748 1/20 0.41
CA9 Q16790 1/20 0.41
HTT P42858 1/20 0.40
AOC3 Q16853 2/20 0.39
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
KEAP1 Q14145 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29006163 1.00 MAOA (0.52) MAOACA7MAOBCA1CA2
SCHEMBL29006168 0.93 CA7 (0.55) MAOACA7MAOBCA1CA2
SCHEMBL29006164 0.93 CA7 (0.55) MAOACA7MAOBCA1CA2
SCHEMBL29006203 0.87 MAOA (0.53) MAOACA7CA1CA2LMNA
SCHEMBL29006200 0.87 MAOA (0.53) MAOACA7CA1CA2LMNA
SCHEMBL29006211 0.87 MAOA (0.55) MAOACA7CA1CA2LMNA
SCHEMBL29006212 0.87 MAOA (0.55) MAOACA7CA1CA2LMNA
SCHEMBL29006221 0.84 MAOA (0.48) MAOACA7CA1CA2LMNA
SCHEMBL29006220 0.84 MAOA (0.48) MAOACA7CA1CA2LMNA
SCHEMBL29006201 0.82 MAOA (0.47) MAOACA7CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178232-A Chiral hydroxy seleno ether and asymmetric synthesis method thereof 湖北滋兰生物医药科技有限公司 2023-05-30 CN disclosed