SCHEMBL29006221

SCHEMBL29006221

OC(C[Se]c1ccccc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.48
PTGS2 P35354 1/20 0.43
LMNA P02545 2/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ACP3 P15309 2/20 0.39
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29006220 1.00 MAOA (0.48) MAOAPTGS2LMNACA1CA2
SCHEMBL29006212 0.88 MAOA (0.55) MAOALMNACA1CA2CA4
SCHEMBL29006211 0.88 MAOA (0.55) MAOALMNACA1CA2CA4
SCHEMBL29006200 0.85 MAOA (0.53) MAOALMNACA1CA2CA4
SCHEMBL29006203 0.85 MAOA (0.53) MAOALMNACA1CA2CA4
SCHEMBL29006198 0.84 MAOA (0.47) MAOALMNACA1CA2CA4
SCHEMBL29006192 0.84 MAOA (0.47) MAOALMNACA1CA2CA4
SCHEMBL29006167 0.84 MAOA (0.52) MAOALMNACA1CA2CA4
SCHEMBL29006201 0.84 MAOA (0.47) MAOALMNACA1CA2CA4
SCHEMBL29006163 0.84 MAOA (0.52) MAOALMNACA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178232-A Chiral hydroxy seleno ether and asymmetric synthesis method thereof 湖北滋兰生物医药科技有限公司 2023-05-30 CN disclosed