SCHEMBL29006173

SCHEMBL29006173

O[C@@H](C[Se]c1ccccc1)c1ccsc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
HTR1A P08908 3/20 0.40
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA4 P22748 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
ALOX5 P09917 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CYP2E1 P05181 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
LMNA P02545 1/20 0.32
ADRB3 P13945 1/20 0.32
RIPK1 Q13546 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29006176 1.00 MAOA (0.44) MAOAHTR1AIDO1TDO2CA1
SCHEMBL29006212 0.80 MAOA (0.55) MAOACA1CA2CA4CA7
SCHEMBL29006211 0.80 MAOA (0.55) MAOACA1CA2CA4CA7
SCHEMBL6954698 0.75 ADRB3 (0.44) HTR1AIDO1TDO2SLC6A2SLC6A3
SCHEMBL29006220 0.74 MAOA (0.48) MAOACA1CA2CA4CA7
SCHEMBL29006221 0.74 MAOA (0.48) MAOACA1CA2CA4CA7
SCHEMBL29006203 0.74 MAOA (0.53) MAOACA1CA2CA4CA7
SCHEMBL29006200 0.74 MAOA (0.53) MAOACA1CA2CA4CA7
SCHEMBL29006201 0.72 MAOA (0.47) MAOAHTR1AIDO1TDO2CA1
SCHEMBL29006151 0.72 MAOA (0.47) MAOACA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178232-A Chiral hydroxy seleno ether and asymmetric synthesis method thereof 湖北滋兰生物医药科技有限公司 2023-05-30 CN disclosed