SCHEMBL29006206

SCHEMBL29006206

O[C@@H](C[Se]c1cccc(Cl)c1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
ACP3 P15309 1/20 0.41
FAAH O00519 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
MAOA P21397 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC2A1 P11166 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30434970 1.00 LMNA (0.48) LMNAADRB2ADRB1ADRB3ACP3
SCHEMBL29006208 1.00 LMNA (0.48) LMNAADRB2ADRB1ADRB3ACP3
SCHEMBL30434135 0.90 ADRB3 (0.50) LMNAADRB2ADRB1ADRB3ACP3
SCHEMBL29006214 0.90 ADRB3 (0.50) LMNAADRB2ADRB1ADRB3ACP3
SCHEMBL29006218 0.90 ADRB3 (0.50) LMNAADRB2ADRB1ADRB3ACP3
SCHEMBL29006212 0.82 MAOA (0.55) LMNAMAOAKDM4EL3MBTL1HIF1A
SCHEMBL29006211 0.82 MAOA (0.55) LMNAMAOAKDM4EL3MBTL1HIF1A
SCHEMBL29006154 0.81 MAOA (0.43) LMNAFAAHMAOAMEN1KMT2A
SCHEMBL29006198 0.81 MAOA (0.47) LMNAMAOAKDM4EL3MBTL1SLC6A2
SCHEMBL29006201 0.81 MAOA (0.47) LMNAMAOAKDM4EL3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178232-A Chiral hydroxy seleno ether and asymmetric synthesis method thereof 湖北滋兰生物医药科技有限公司 2023-05-30 CN disclosed