Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.59 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594322 | 0.94 | LOXL2 (0.65) | ATMTDP1L3MBTL1LOXL2PBRM1 | |
| SCHEMBL203283 | 0.86 | ALDH1A1 (0.61) | ATMTDP1L3MBTL1LOXL2PBRM1 | |
| SCHEMBL10905589 | 0.85 | ATM (0.59) | ATMTDP1L3MBTL1LOXL2PBRM1 | |
| Hydrochloric Acid SCHEMBL2450035 | 0.84 | ALDH1A1 (0.58) | ATMTDP1L3MBTL1LOXL2PBRM1 | |
| SCHEMBL31500915 | 0.84 | FOLH1 (0.66) | LOXL2CYP2D6CYP2C9ENPP2CA1 | |
| SCHEMBL61226 | 0.84 | FOLH1 (0.66) | LOXL2CYP2D6CYP2C9ENPP2CA1 | |
| SCHEMBL31500919 | 0.84 | FOLH1 (0.66) | LOXL2CYP2D6CYP2C9ENPP2CA1 | |
| Benzoic Acid SCHEMBL10764505 | 0.82 | LOXL2 (0.56) | LOXL2CFDSRD5A2CYP1A2CYP2D6 | |
| Water SCHEMBL8887800 | 0.82 | FOLH1 (0.63) | LOXL2CYP2D6CYP2C9ENPP2FOLH1 | |
| Hydrochloric Acid SCHEMBL4232340 | 0.82 | FOLH1 (0.63) | LOXL2CYP2D6CYP2C9ENPP2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9169710-A | — | — | None | — | — | JP | disclosed |
| US-20120053165-A1 | Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators | PFIZER INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120053165-A1 | Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators | PFIZER INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20100298324-A1 | Prolyl Hydroxylase Inhibitors | SMITH KLINE BEECHAM CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2240178-A1 | PROLYL HYDROXYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2010100606-A1 | NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS | PFIZER INC. (US) | 2010-09-10 | — | — | WO | disclosed |
| WO-2009086044-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITH KLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| JP-H09169710-A | ANTIFUNGAL AGENT AND COMPOSITION CONTAINING THE SAME | POLA CHEM IND INC | 1997-06-30 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298324-A1 | Prolyl Hydroxylase Inhibitors | HIF1AN, EGLN3, EGLN2 | ATM 4425/4885TDP1 2164/4885L3MBTL1 2188/4885 |
| US-20120053165-A1 | Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators | BACE1, BACE2, PSEN1 | ATM 1087/4885TDP1 390/4885L3MBTL1 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.