SCHEMBL29007199

SCHEMBL29007199

C=CCOC(=O)C1=CC=CC1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 1/20 0.45
SNCA P37840 1/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 2/20 0.38
TP53 P04637 1/20 0.38
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
RHOA P61586 1/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11499570 0.83 CYP3A4 (0.45) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL15802674 0.80 TSHR (0.35) CYP3A4ALDH1A1TSHRCA1CA2
SCHEMBL6433950 0.79 CYP3A4 (0.44) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL11813670 0.79 CYP3A4 (0.41) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL11813677 0.79 CYP3A4 (0.41) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL11818485 0.79 CYP3A4 (0.41) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL8947546 0.78 TSHR (0.48) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL28417053 0.78 TSHR (0.48) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL15802763 0.77 KDM4E (0.30) KDM4E
SCHEMBL28408947 0.75 ALDH1A1 (0.52) CYP3A4ALDH1A1HSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524944-B Synthesis of tertiary amine end-capped environment-friendly hyperbranched polyamine intercalation inhibitor and water-based drilling fluid 成都昂赛福科技有限公司 2023-05-26 CN disclosed